TORCH infections in women of childbearing potential and pregnant women: risk factors, diagnosis, and seroprevalence

Authors

Keywords:

congenital infections; TORCH; women; pregnancy; fertile age.

Abstract

Women present a series of characteristics that define not only their health and well-being, but also become positive or negative predictors of the health of future generations, hence the purpose of the topic to be investigated, which aims to demonstrate infections by TORCH in pregnant women of childbearing age: risk factors, diagnosis, and seroprevalence. In this context,  the applied methodology was descriptive, documentary and it was based on the search for articles: in the Pubmed, Scielo, Elsevier, Google Scholar, Redalyc databases, in which the MeSH terms, "congenital infections", "TORCH", " toxoplasmosis”, “infections”, “pregnancy”, “Rubella”, “herpes”, “cytomegalovirus”, “childbearing age”, “women”. The results obtained are focused on the determination of the various risk factors, among which socioeconomic level, geographical location, poor eating habits and age stand out, highlighting the most prevalent laboratory techniques in the diagnosis of TORCH infections, which are the enzyme-linked immunoassay (ELISA) and enzyme immunoassays of chemiluminescent microparticles Besides,  there were positive results for active infections in regions such as Europe, Asia and Latin America, among which it stands out that these infections have been contracted due to the high seroprevalence of igg antibodies in study populations. In conclusion, TORCH infections are prevalent worldwide, affecting women of childbearing age and pregnant women, mainly highlighting socioeconomic factors, so this population group should be encouraged to monitor before and during pregnancy, thus avoiding congenital diseases.

Downloads

Download data is not yet available.

References

Adgoy, E. T., Elfatih, M., Elhadi, B., Zerizgie, H., Said, S. M., Tekle, F., & Andemariam, Z. (2020). Seroprevalence of TORCH in women with spontaneous abortion and stillbirth, in Asmara, Eritrea. Population Medicine, 2(November), 1-5. Retrieved from http://www.populationmedicine.eu/Seroprevalence-of-TORCH-in-women-with-spontaneous-abortion-and-stillbirth-in-Asmara,128008,0,2.html

Al-Hakami, A. M., Paul, E., Al-Abed, F., Alzoani, A. A., Shati, A. A., Assiri, M. I., . . . Chandramoorthy, H. C. (2020). Prevalence of toxoplasmosis, rubella, cytomegalovirus, and herpes (TORCH) infections among women attending the antenatal care clinic, maternity hospital in Abha, Southwestern Saudi Arabia. Saudi Medical Journal, 41(7), 757. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7502919/

Al-Shammari, N., & Iqbal, J. (2021). Decreasing trend in Toxoplasma seroprevalence among pregnant women in Kuwait. Eastern Mediterranean Health Journal, 27(1), 67-75. Retrieved from https://apps.who.int/iris/bitstream/handle/10665/352143/1020-3397-2021-2701-67-75-eng.pdf?sequence=1

Albayrak, H. T., Bakır, A., Güney, M., & Yavuz, M. T. (2020). Evaluation of Toxoplasma gondii, Rubella virus and Cytomegalovirus Infections. The Anatolian Journal of Family Medicine, 3(2), 136. Retrieved from https://jag.journalagent.com/anatoljfm/pdfs/ANATOLJFM-22932-ORIGINAL_RESEARCH-ALBAYRAK.pdf

Almaghrabi, M. K., Alwadei, A. D., Alyahya, N. M., Alotaibi, F. M., Alqahtani, A. H., Alahmari, K. A., . . . Ali, A. S. (2019). Seroprevalence of Human cytomegalovirus in pregnant women in the Asir region, Kingdom of Saudi Arabia. Intervirology, 62(5-6), 205-209. Retrieved from https://www.karger.com/Article/FullText/506051

Alvarado-Esquivel, C., del Carmen Terrones-Saldivar, M., Hernandez-Tinoco, J., Munoz-Terrones, M. D. E., Gallegos-Gonzalez, R. O., Sanchez-Anguiano, L. F., . . . Antuna-Salcido, E. I. (2018). Seroepidemiology of cytomegalovirus infection in pregnant women in the Central Mexican City of Aguascalientes. Journal of Clinical Medicine Research, 10(4), 337. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827919/

Alzaheb, R. A., & Al-Amer, O. (2017). The seroprevalence and risk factors of toxoplasmosis among female undergraduate university students in Saudi Arabia. Oman medical journal, 32(6), 486. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702993/

Ambou Frutos, I., Lastra Pérez, L., Vilches Lescaille, D., Osorio Illas, L., Ramos López, M., & Rodríguez Ahuar, N. (2018). Manifestaciones clínicas asociadas al síndrome de TORCH. Revista Cubana de Oftalmología, 31(1), 132-144. Retrieved from http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-21762018000100013

Antona, D., Lepoutre, A., Fonteneau, L., Baudon, C., Halftermeyer-Zhou, F., Le Strat, Y., & Lévy-Bruhl, D. (2017). Seroprevalence of cytomegalovirus infection in France in 2010. Epidemiology & Infection, 145(7), 1471-1478. Retrieved from https://www.cambridge.org/core/services/aop-cambridge-core/content/view/FBEF04F5E2A1F155B5AD515D67D85070/S0950268817000103a.pdf/seroprevalence-of-cytomegalovirus-infection-in-france-in-2010.pdf

Barbosa, N. G., Yamamoto, A. Y., Duarte, G., Aragon, D. C., Fowler, K. B., Boppana, S., . . . Mussi-Pinhata, M. M. (2018). Cytomegalovirus shedding in seropositive pregnant women from a high-seroprevalence population: the Brazilian cytomegalovirus hearing and maternal secondary infection study. Clinical Infectious Diseases, 67(5), 743-750. Retrieved from https://academic.oup.com/cid/article/67/5/743/4911485

Bieńkowski, C., Aniszewska, M., Kowalczyk, M., Popielska, J., Zawadka, K., Ołdakowska, A., & Pokorska-Śpiewak, M. (2022). Analysis of Preventable Risk Factors for Toxoplasma gondii Infection in Pregnant Women: Case-Control Study. Journal of Clinical Medicine, 11(4), 1105. Retrieved from https://www.mdpi.com/2077-0383/11/4/1105/pdf

Cofre, F., Delpiano, L., Labraña, Y., Reyes, A., Sandoval, A., & Izquierdo, G. (2016). Síndrome de TORCH: enfoque racional del diagnóstico y tratamiento pre y post natal. Recomendaciones del Comité Consultivo de Infecciones Neonatales Sociedad Chilena de Infectología, 2016. Revista chilena de infectología, 33(2), 191-216. Retrieved from https://www.scielo.cl/scielo.php?pid=S0716-10182016000200010&script=sci_arttext&tlng=pt

Costa, G. B., De Oliveira, M. C., Gadelha, S. R., Albuquerque, G. R., Teixeira, M., da Silva Raiol, M. R., . . . Marin, L. J. (2018). Infectious diseases during pregnancy in Brazil: seroprevalence and risk factors. The Journal of Infection in Developing Countries, 12(08), 657-665. Retrieved from https://jidc.org/index.php/journal/article/download/31958329/1920

Covarrubias, N., Vera, D. B., & Hurtado, C. (2020). Seroprevalencia de Toxoplasma gondii en un hospital universitario en Chile. Revista chilena de infectología, 37(6), 784-787. Retrieved from https://www.scielo.cl/scielo.php?pid=S0716-10182020000600784&script=sci_arttext

Chávez, J. A. D., Castillo, A. d. R. P., Alcocer, D. A. Q., Flores, W. Y. G., Puga, M. E. J., & Buitrón, D. E. O. (2018). Cribado de toxoplasmosis en mujeres embarazadas en el Hospital Básico Provida. Latacunga 2013-2016. Revista de la Facultad de Ciencias Médicas de la Universidad de Cuenca, 36(1), 35-42. Retrieved from https://publicaciones.ucuenca.edu.ec/ojs/index.php/medicina/article/download/1573/1590

Chen, L., Liu, J., Shi, L., Song, Y., Song, Y., Gao, Y., . . . Zhai, Y. (2019). Seasonal influence on TORCH infection and analysis of multi‐positive samples with indirect immunofluorescence assay. Journal of clinical laboratory analysis, 33(4), e22828. Retrieved from https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jcla.22828

Choi, R., Oh, Y., Oh, Y., Kim, S. H., Lee, S. G., & Lee, E. H. (2020). Recent trends in seroprevalence of rubella in Korean women of childbearing age: a cross-sectional study. BMJ open, 10(1), e030873. Retrieved from https://bmjopen.bmj.com/content/10/1/e030873.abstract

De Carolis, S., Tabacco, S., Rizzo, F., Perrone, G., Garufi, C., Botta, A., . . . Lanzone, A. (2018). Association between false-positive TORCH and antiphospholipid antibodies in healthy pregnant women. Lupus, 27(5), 841-846. Retrieved from https://journals.sagepub.com/doi/full/10.1177/0961203317741564

Deka, S., Kalita, D., Paul, M., Badoni, G., & Mathuria, Y. P. (2022). Seroprevalence and Determinants of ToRCH Pathogens in Pregnant Women in the Sub-Himalayan Region. Cureus, 14(2). Retrieved from https://www.cureus.com/articles/77892-seroprevalence-and-determinants-of-torch-pathogens-in-pregnant-women-in-the-sub-himalayan-region

Domercant, J. W., Jean Louis, F., Hulland, E., Griswold, M., Andre-Alboth, J., Ye, T., & Marston, B. J. (2017). Seroprevalence of Herpes Simplex Virus type-2 (HSV-2) among pregnant women who participated in a national HIV surveillance activity in Haiti. BMC infectious diseases, 17(1), 1-7. Retrieved from https://link.springer.com/article/10.1186/s12879-017-2674-4

Fuchs, F. E., Pauly, M., Black, A. P., & Hübschen, J. M. (2021). Seroprevalence of ToRCH Pathogens in Southeast Asia. Microorganisms, 9(3), 574. Retrieved from https://www.mdpi.com/2076-2607/9/3/574/pdf

Goidescu, I., Goidescu, C. M., Nemeti, G., Popa, I., Surcel, M., Cruciat, G., & Mureșan, D. (2011). Acute CMV infection in pregnancy. Respectă Echilibrul Natural1, 2, 17, 172. Retrieved from https://www.medichub.ro/upload/magazines/464_b9f4a7dc0bef18060c1908e5cbc18d4d.pdf?utm_source=newsletter&utm_medium=email&utm_content=Newsletter-85343520210112&utm_campaign=A+aparut+noul+numar+al+revistelor+%E2%80%9DGinecologia.ro%E2%80%9D+si+%E2%80%9DObstetrica+si+Ginecologia%E2%80%9D#page=16

Gonca, S., Serin, M. S., Halepliler, S., & Ertürk, S. E. (2021). Mersin’de Bir Devlet Hastanesine Başvuran Gebelerde Toxoplasma gondii Seroprevalansı, 2019. Türkiye Parazitolojii Dergisi, 45(3), 176. Retrieved from https://cms.galenos.com.tr/Uploads/Article_48449/TPD-45-176.pdf

González, A., Camejo, M., & Castillo, Y. (2017). Seroprevalencia de toxoplasmosis en pacientes femeninos que asisten a la red ambulatoria del municipio Francisco Linares Alcántara, Maracay, estado Aragua, Venezuela. Kasmera, 45(2), 119-127. Retrieved from https://www.redalyc.org/journal/3730/373061523006/373061523006.pdf

Halici-Ozturk, F., Yakut, K., Öcal, F. D., Erol, A., Gökay, S., Çağlar, A. T., . . . Ozgu-Erdinc, A. S. (2021). Seroprevalence of Toxoplasma gondii infections in Syrian pregnant refugee women in Turkey. European Journal of Obstetrics & Gynecology and Reproductive Biology, 256, 91-94. Retrieved from https://www.sciencedirect.com/science/article/pii/S0301211520307053

Hoehl, S., Berger, A., Ciesek, S., & Rabenau, H. F. (2020). Thirty years of CMV seroprevalence—a longitudinal analysis in a German university hospital. European Journal of Clinical Microbiology & Infectious Diseases, 39(6), 1095-1102. Retrieved from https://link.springer.com/article/10.1007/s10096-020-03814-x

Huang, Y., Guo, X., Song, Q., Wang, H., Yu, H., Zhang, Y., . . . Zhuang, S. (2018). Cytomegalovirus shedding in healthy seropositive female college students: a 6-month longitudinal study. The Journal of Infectious Diseases, 217(7), 1069-1073. Retrieved from https://academic.oup.com/jid/article/217/7/1069/4774530

Jin, Q. e., Su, J., & Wu, S. (2017). Cytomegalovirus infection among pregnant women in Beijing: seroepidemiological survey and intrauterine transmissions. Journal of microbiology and biotechnology, 27(5), 1005-1009. Retrieved from https://www.koreascience.or.kr/article/JAKO201718054814345.pdf

Kumar, H., Singh, V., Isha, M., Mehta, S., Garg, R., & Shinu, P. (2018). Line Immunoassay: A Rapid Test for Screening TORCH Complex in Antenatal Patients with Bad Obstetric History. Mymensingh medical journal: MMJ, 27(3), 641-644. Retrieved from https://europepmc.org/article/med/30141457

Lachmann, R., Loenenbach, A., Waterboer, T., Brenner, N., Pawlita, M., Michel, A., . . . Wiese-Posselt, M. (2018). Cytomegalovirus (CMV) seroprevalence in the adult population of Germany. PloS one, 13(7), e0200267. Retrieved from https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0200267

Lima, L. R. P., Almeida, N. A. A., Horta, M. A. P., Belo, V. S., da Silva, A. S., Capelin, G. J. M., . . . Tanaka, T. S. O. (2021). Human alphaherpesvirus 2 (HSV-2) among female sex workers from Brazil: cross-sectional study using respondent-driven sampling. Sexually Transmitted Infections, 97(6), 461-464. Retrieved from https://www.arca.fiocruz.br/bitstream/icict/45713/2/LianaRPLima_VanessaSPaula_etal_IOC_2020.pdf

López-Regalado, M. L., Clavero, A., Gonzalvo, M. C., Serrano, M., Martínez, L., Mozas, J., . . . Castilla, J. A. (2014). Randomised clinical trial comparing elective single-embryo transfer followed by single-embryo cryotransfer versus double embryo transfer. European Journal of Obstetrics & Gynecology and Reproductive Biology, 178, 192-198. Retrieved from https://www.sciencedirect.com/science/article/pii/S0301211514002188

Manjunathachar, H., Singh, K. N., Chouksey, V., Kumar, R., Sharma, R. K., & Barde, P. V. (2020). Prevalence of torch infections and its associated poor outcome in high-risk pregnant women of central India: time to think for prevention strategies. Indian journal of medical microbiology, 38(3-4), 379-384. Retrieved from https://www.sciencedirect.com/science/article/pii/S0255085720315474/pdf?md5=aff6106ed82c1a97990e0495bc46b929&pid=1-s2.0-S0255085720315474-main.pdf

Mar-Cornelio, O., Ramírez-Pérez, J. F., López-Cossio, F., Morejón, M. M., & Orellana-García, A. (2021). Impacto de la Maestría en Informática Médica Aplicada en la informatización de la salud pública cubana. Revista Información Científica, 100(2). Retrieved from http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1028-99332021000200013

Markon, A., Ryan, K., Wadhawan, A., Pavlovich, M., Groer, M., Punzalan, C., . . . Dagdag, A. (2021). Risk factors for Toxoplasma gondii seropositivity in the Old Order Amish. Epidemiology & Infection, 149. Retrieved from https://www.cambridge.org/core/services/aop-cambridge-core/content/view/15AE4881AA6E6070412C4C09B54AED1A/S0950268820002897a.pdf/div-class-title-risk-factors-for-span-class-italic-toxoplasma-gondii-span-seropositivity-in-the-old-order-amish-div.pdf

Mhandire, D., Duri, K., Kaba, M., Mhandire, K., Musarurwa, C., Chimusa, E., . . . Dandara, C. (2019). Seroprevalence of cytomegalovirus infection among HIV-infected and HIV-uninfected pregnant women attending antenatal clinic in Harare, Zimbabwe. Viral immunology, 32(7), 289-295. Retrieved from https://www.liebertpub.com/doi/full/10.1089/vim.2019.0024

Mhandire, D., Rowland-Jones, S., Mhandire, K., Kaba, M., & Dandara, C. (2019). Epidemiology of Cytomegalovirus among pregnant women in Africa. The Journal of Infection in Developing Countries, 13(10), 865-876. Retrieved from https://ora.ox.ac.uk/objects/uuid:3004dec4-8c91-4802-9640-1f91f7c08881/download_file?file_format=pdf&safe_filename=Mhandire%2Bet%2Bal%2BEpidemiology%2Bof%2Bcytomegalovirus%2Bamong%2Bpregnant%2Bwomen%2Bin%2BAfrica.pdf&type_of_work=Journal+article

Mocanu, A. G., Gorun, F., Ciohat, I., Navolan, D., Malita, D., Vilibic-Cavlek, T., . . . Cioca, A. (2021). Simultaneous Seroprevalence to Toxoplasma gondii, Cytomegalovirus and Rubella Virus in Childbearing Women from Western Romania. Medicina, 57(9), 927. Retrieved from https://www.mdpi.com/1648-9144/57/9/927/htm

Nereida Josefina, V.-C., José Daniel, L.-G., Esteban Leonardo, G.-Z., & Teresa Isabel, V.-C. (2021). Infecciones por TORCH y Parvovirus B19 humano en mujeres embarazadas: implicaciones terapéuticas y de diagnóstico. Revisión Sistemática. Revista Kasmera, 49. Retrieved from https://search.ebscohost.com/login.aspx?direct=true&profile=ehost&scope=site&authtype=crawler&jrnl=00755222&AN=155390920&h=w2JGrOj4YosXd%2BAFxX6u6%2FE%2BWK0dpHoaoQg7ool77%2B5Jrn9UGh1j5TQdewpR6iLslWPzLJ%2BU%2BAyBNob6EivWNg%3D%3D&crl=c

Nóbrega, Y. K., de Carvalho, B. C., Nitz, N., Vital, T. E., Leite, F. B., Sequeira, I. J., . . . Pratesi, R. (2017). Rubella Seropositivity in Pregnant Women After Vaccination Campaign in Brazil's Federal District. Viral immunology, 30(9), 675-677. Retrieved from https://www.liebertpub.com/doi/abs/10.1089/vim.2017.0012

Olarinde, O., Sowemimo, O. A., Chuang, T.-W., Chou, C.-M., Olasanmi, S. O., Ikotun, K., . . . Olukosi, A. Y. (2022). Toxoplasma gondii infection: seroprevalence and associated risk factors for women of childbearing age in Osun State, Nigeria. Pathogens and Global Health, 116(1), 59-65. Retrieved from https://www.tandfonline.com/doi/abs/10.1080/20477724.2021.1949193

Olariu, T. R., Ursoniu, S., Hotea, I., Dumitrascu, V., Anastasiu, D., & Lupu, M. A. (2020). Seroprevalence and risk factors of Toxoplasma gondii infection in pregnant women from Western Romania. Vector-Borne and Zoonotic Diseases, 20(10), 763-767. Retrieved from https://www.liebertpub.com/doi/abs/10.1089/vbz.2019.2599

Rezabala, D. J. G., López, K. A. Z., Cedeño, N. J. V., & Magallanes, J. J. C. (2022). Prevalencia inmunidad a TORCH en mujeres embarazadas en el cantón Olmedo. Ciencia Latina Revista Científica Multidisciplinar, 6(2), 351-372. Retrieved from https://ciencialatina.org/index.php/cienciala/article/download/1889/2691

Saajan, A. M., Nyindo, M., Gidabayda, J. G., Abdallah, M. S., Jaffer, S. H., Mukhtar, A. G., . . . Mmbaga, B. T. (2017). TORCH Antibodies Among Pregnant Women and Their Newborns Receiving Care at Kilimanjaro Christian Medical Centre, Moshi, Tanzania. The East African Health Research Journal, 1(2), 95. Retrieved from https://www.ajol.info/index.php/eahrj/article/download/217932/205538

Salamanca-Rojas, S., Barahona-López, N. M., Marín-Valcárcel, A., Vidal-Camargo, P. A., Pedraza-Bernal, A. M., Ramírez-Rueda, R. Y., & Jaimes-Bernal, C. P. (2018). Seroprevalence of anti-rubella and anti-cytomegalovirus IgG antibodies in women aged between 16 and 40 years, living in Tunja, Colombia. Revista de Salud Pública, 20(4), 479-483. Retrieved from http://www.scielo.org.co/pdf/rsap/v20n4/0124-0064-rsap-20-04-479.pdf

Sánchez Artigas, R., Araujo Baptista, L., Brossard Peña, E., Atair Falconi, F., Ramos Campi, Y., & Barba Maggi, M. A. (2018). Prevalencia de toxoplasmosis en estudiantes de la Universidad Nacional de Chimborazo en Ecuador. Revista Cubana de Investigaciones Biomédicas, 37(2), 117-126. Retrieved from http://scielo.sld.cu/scielo.php?pid=S0864-03002018000200013&script=sci_arttext&tlng=pt

Sánchez Artigas, R., Barba Maggi, M. A., Ramos Campi, Y. C., & Brossard Peña, E. (2020). Algunas variables epidemiológicas relacionadas con la toxoplasmosis en mujeres en edad fértil en Riobamba. Revista Cubana de Investigaciones Biomédicas, 39(1). Retrieved from http://scielo.sld.cu/scielo.php?pid=S0864-03002020000100014&script=sci_arttext&tlng=en

Shahapur, P. R., & Kandi, V. (2020). Seroprevalence of Rubella virus-specific antibodies in women and the diagnostic efficacy of enzyme-linked immunoassay and rapid immunochromatographic tests. Cureus, 12(3). Retrieved from https://www.cureus.com/articles/28061-seroprevalence-of-rubella-virus-specific-antibodies-in-women-and-the-diagnostic-efficacy-of-enzyme-linked-immunoassay-and-rapid-immunochromatographic-tests

Trombetta, C. M., Viviani, S., Montomoli, E., & Marchi, S. (2021). Seroprevalence of antibodies to cytomegalovirus in pregnant women in the Apulia region (Italy). Journal of Preventive Medicine and Hygiene, 62(2), E372. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8451340/

Velásquez Serra, G., Piloso Urgiles, L., Guerrero Cabredo, B., Chico Caballero, M., Zambrano Zambrano, S., Yaguar Gutierrez, E., & Barrera Reyes, C. (2020). Current Situation of Congenital Toxoplasmosis in Ecuador. Journal of Community Health, 45(1), 170-175. Retrieved from https://link.springer.com/article/10.1007/s10900-019-00729-3

Vilajeliu, A., García-Basteiro, A. L., Valencia, S., Barreales, S., Oliveras, L., Calvente, V., . . . Bayas, J. M. (2015). Rubella susceptibility in pregnant women and results of a postpartum immunization strategy in Catalonia, Spain. Vaccine, 33(15), 1767-1772. Retrieved from http://diposit.ub.edu/dspace/bitstream/2445/99514/6/vilajeliu2015_1825.pdf

Vivanco, M. L., Osorio, M. B. S., Luna, J. S., Galvan, D. S., & Bravo, M. L. (2016). Toxoplasma gondii en mujeres embarazadas en la provincia de El Oro, 2014/Toxoplasma gondii in pregnant women in the province of El Oro, 2014. Revista ciencia UNEMI, 9(21), 135-141. Retrieved from https://dialnet.unirioja.es/descarga/articulo/8377229.pdf

Zahir, H., Arsalane, L., Elghouat, G., Mouhib, H., Elkamouni, Y., & Zouhair, S. (2020). Seroprevalence of rubella in pregnant women in Southern Morocco. The Pan African Medical Journal, 35(Suppl 1). Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7195913/

Zenebe, M. H., Mekonnen, Z., Loha, E., & Padalko, E. (2021). Seroprevalence and associated factors of maternal cytomegalovirus in Southern Ethiopia: a cross-sectional study. BMJ open, 11(10), e051390. Retrieved from https://bmjopen.bmj.com/content/11/10/e051390.abstract

Zhou, Q., Wang, Q., Shen, H., Zhang, Y., Zhang, S., Li, X., & Acharya, G. (2021). Seroprevalence of Cytomegalovirus and Associated Factors Among Preconception Women: A Cross-Sectional Nationwide Study in China. Frontiers in public health, 9. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425481/

Published

2023-01-23

How to Cite

Sánchez Menéndez , A. J. ., Sornoza Rosado, G. N., & Castro Jalca , J. E. . (2023). TORCH infections in women of childbearing potential and pregnant women: risk factors, diagnosis, and seroprevalence . Revista Científica Arbitrada Multidisciplinaria PENTACIENCIAS - ISSN 2806-5794., 5(1), 286–306. Retrieved from https://editorialalema.org/index.php/pentaciencias/article/view/445

Issue

Section

Artículos de revisión